Thursday, August 28
Welcome address
09:00-09:05 Weng-Onn Lui, John Paoli, Nicole Fischer, Jürgen Becker, Lisa Villabona & Thibault Kervarrec
Session I: Merkel cell polyomavirus and oncogenesis
Chair: Nicole Fischer (Hamburg-Eppendorf, Germany) and Ugo Moens (Tromsø, Norway)
09:05-09:35 Denise Galloway (Seattle, WA, USA)
Does ALTO contribute to MCPyV latency?
09:35-10:05 Etienne Coyaud (Lille, France)
Exploring the molecular mechanisms of MCC oncogenes through proximal interactomics
10:05-10:35 John Charles Rotondo (Genoa, italy)
Epigenetic dysregulation in MCC: a potential therapeutic target
10:35-10:50 Isaac Brownell (Bethesda, MD, USA)
The paranuclear dot as a regulator of extrinsic apoptosis
10:50-11:20 Coffee break
11:20-11:35 Amanda Macamo (Maastricht, The Netherlands)
Title TBD
11:35-12:00 Flash poster presentations (2 minutes/presentation)
Krista Lachance and Rima Kulikauskas (Seattle, WA, USA), Brendan McCann (Glasgow, Scotland, UK), Candice Church (Seattle, WA, USA), Sara Passerini (Rome, Italy), Valeria Antonietta Pietropaolo (Rome, Italy), Xiaohao Wang (Stockholm, Sweden), Büke Celikdemir (Turkey) and Peter Ch’en (Seattle, WA, USA).
12:00-12:45 Poster session
12:45-13:45 Lunch
Session II: Immunobiology and tumor microenvironment
Chairs: Thibault Kervarrec (Tours, France) and John Paoli (Gothenburg, Sweden)
13:45-14:15 Maximilian Haist (Palo Alto, CA, USA)
MCPyV-linked spatial Immunomodulation of the MCC tumor microenvironment and its impact on patient survival
14:15-14:45 Jaehyuk Choi (Dallas, TX, USA)
Title TBD
14:45-15:15 Göran Jönsson (Lund, Sweden)
Title TBD
15:15-15:45 Coffee break
15:45-16:00 Tomas Bencomo (Seattle, WA, USA)
Spatial transcriptomics analysis of MCC reveals tumor-intrinsic factors involved in T cell exclusion
16:00-16:15 Paul Harms (Ann Arbor, MI, USA)
The Diagnostic Utility of H3K27Me3 Immunohistochemistry for Merkel Cell Carcinoma
16:15-16:30 Haroldo Rodríguez (Seattle, WA, USA)
Title TBD