Section III: Emerging technologies/models for MCC research

Chair: Weng-Onn Lui (Stockholm, Sweden) and Axel zur Hausen (Maastricht, The Netherlands)

09:00-09:30 Camilla Engblom (Stockholm, Sweden)
Mapping antigen receptors in tissues using spatial transcriptomics

09:30-10:00    Simon Fredriksson (Stockholm, Sweden)
Protein interactomics of single cells by Proximity Networks for translational research

10:00-10:30    Tobias Reiff (Düsseldorf, Germany)
Personalized fly avatar technology for the investigation of tumour biology and therapy development

10:30-11:00    Coffee break   

11:00-11:15   Megha Padi (Tucson, AZ, USA)
Translating network biology into new therapies for MCC

11:15-11:30   Krista Lachance, Rima Kulikauskas, Candice Church and Paul Nghiem (Seattle, WA, USA)
How can the Merkel cell carcinoma collaborative (MC3) Institute help advance our field?

Session IV: Immunotherapy and clinical trials

Chair: Jürgen Becker (Essen, Germany) and Lisa Villabona (Stockholm, Sweden)

11:30-12:00    Anna-Sophia Leven (Essen, Germany) presented by George Lodde (Essen, Germany)
Adjuvant and neo-adjuvant therapy of MCC

12:00-12:30    Shailender Bhatia (Seattle, WA, USA)
Intra-tumoral immunotherapies for MCC

12:30-13:30    Lunch                

13:30-14:00    Céleste Lebbé (Paris, France)
Immunotherapy in Advanced MCC: Clinical Impact and Evidence from Clinical Trials and Real-World Data

14:00-14:30    Aubriana McEvoy, Lisa Zaba, Peter Ch’en and Paul Nghiem (St. Louis, MO; Stanford, CA; Seattle, WA, USA)
Multicenter collaboration opportunities: upcoming MC3 studies on risk, radiation, and refractoriness

14:30-14:45   George Lodde (Essen, Germany)
Survival Outcome of MCC’s initial locoregional treatment in the pre- and immunotherapy era

14:45-15:00   Kelly Harms (Ann Arbor, MI, USA)
Adjuvant single fraction radiotherapy to the resected primary tumor site and stage IIIA regional disease results in high locoregional control in MCC

15:00-15:05    Short break 

15:05-15:30   Merrick Ross (Houston, TX, USA)
Case discussions

Final remarks

15:30-15:45    Weng-Onn Lui, John Paoli, Nicole Fischer, Jürgen Becker, Lisa Villabona & Thibault Kervarrec